Overview

  • Product name
    Anti-PGGT1B antibody
  • Description
    Rabbit polyclonal to PGGT1B
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence, corresponding to amino acids 213-347 of Human PGGT1B.

  • Positive control
    • Human breast tissue; RT 4, U 251 MG, Human liver and tonsil lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding.
  • Sequence similarities
    Belongs to the protein prenyltransferase subunit beta family.
    Contains 4 PFTB repeats.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • BGGI antibody
    • Geranylgeranyl transferase type I subunit beta antibody
    • Geranylgeranyl transferase type-1 subunit beta antibody
    • Geranylgeranyltransferase type I beta subunit antibody
    • GGTase-I-beta antibody
    • GGTI antibody
    • PGGT1B antibody
    • PGTB1_HUMAN antibody
    • Protein geranylgeranyltransferase type I, beta subunit antibody
    • Type I protein geranyl-geranyltransferase subunit beta antibody
    see all

Images

  • Western blot - Anti-PGGT1B antibody (ab122122)
    Western blot - Anti-PGGT1B antibody (ab122122)
    Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGGT1B antibody (ab122122)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGGT1B antibody (ab122122)
    ab122122, at a 1/75 dilution, staining PGGT1B in paraffin-embedded Human breast tissue by Immunohistochemistry.
  • Western blot - Anti-PGGT1B antibody (ab122122)
    Western blot - Anti-PGGT1B antibody (ab122122)
    All lanes : Anti-PGGT1B antibody (ab122122) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique.

References

ab122122 has not yet been referenced specifically in any publications.

Publishing research using ab122122? Please let us know so that we can cite the reference in this datasheet.

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