Overview

  • Product name

  • Description

    Goat polyclonal to PGK1
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PGK1 aa 321-333 (internal sequence) (Cysteine residue). NP_000282.1
    Sequence:

    SKKYAEAVTRAKQ


    Database link: P00558

  • Positive control

    • HeLa, A432, HEK293 and HepG2 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab190291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

Target

  • Function

    In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
  • Pathway

    Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.
  • Involvement in disease

    Defects in PGK1 are the cause of phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653]. It is a condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations.
  • Sequence similarities

    Belongs to the phosphoglycerate kinase family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cell migration-inducing gene 10 protein antibody
    • Epididymis secretory sperm binding protein Li 68p antibody
    • HEL S 68p antibody
    • MGC117307 antibody
    • MGC8947 antibody
    • MIG10 antibody
    • pgk1 antibody
    • PGK1_HUMAN antibody
    • PGKA antibody
    • Phosphoglycerate kinase 1 antibody
    • Primer recognition protein 2 antibody
    • PRP 2 antibody
    see all

Images

  • Anti-PGK1 antibody (ab190291) at 0.1 µg/ml + HeLa cell lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 45 kDa


    Exposure time: 1 hour

References

ab190291 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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