Anti-PGP9.5 antibody [13C4 / I3C4] (ab8189)

Knockout Tested Mouse monoclonal PGP9.5 antibody [13C4 / I3C4]. Validated in WB, IHC, ICC, ICC/IF and tested in Mouse, Rat, Sheep, Rabbit, Guinea pig, Dog, Human, Pig, Zebrafish.

Publishing research using ab8189? Please let us know so that we can cite the reference in this datasheet.

ab8189 has been referenced in 53 publications.

  • Marini M  et al. Immunolocalization of VEGF/VEGFR system in human fetal vomeronasal organ during early development. Acta Histochem 121:94-100 (2019). PubMed: 30442382
  • Liu Z  et al. Fractalkine/CX3CR1 Contributes to Endometriosis-Induced Neuropathic Pain and Mechanical Hypersensitivity in Rats. Front Cell Neurosci 12:495 (2018). PubMed: 30622457
  • Xiong Y  et al. Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide-induced intestinal injury. Mol Med Rep 18:2171-2181 (2018). PubMed: 29901151
  • Zhang M  et al. Bilateral sympathetic stellate ganglionectomy attenuates myocardial remodelling and fibrosis in a rat model of chronic volume overload. J Cell Mol Med N/A:N/A (2018). PubMed: 30411499
  • Hill RZ  et al. The signaling lipid sphingosine 1-phosphate regulates mechanical pain. Elife 7:N/A (2018). PubMed: 29561262
  • Pinho-Ribeiro FA  et al. Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection. Cell 173:1083-1097.e22 (2018). PubMed: 29754819
  • Ouyang Z  et al. Differential Innervation of Secretory Coils and Ducts in Human Eccrine Sweat Glands. Chin Med J (Engl) 131:1964-1968 (2018). PubMed: 30082528
  • Bai J  et al. Octreotide modulates the expression of somatostatin receptor subtypes in inflamed rat jejunum induced by Cryptosporidium parvum. PLoS One 13:e0194058 (2018). PubMed: 29522573
  • De Logu F  et al. Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice. Nat Commun 8:1887 (2017). PubMed: 29192190
  • Kviesulaitis V  et al. Heart rate variability after radiofrequency ablation of epicardial ganglionated plexuses on the ovine left atrium. BMC Cardiovasc Disord 17:292 (2017). PubMed: 29233092
  • Koudy Williams J  et al. Efficacy and Initial Safety Profile of CXCL12 Treatment in a Rodent Model of Urinary Sphincter Deficiency. Stem Cells Transl Med 6:1740-1746 (2017). PubMed: 28714578
  • Uchida H  et al. A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells. JCI Insight 2:e86492 (2017). PubMed: 28097227
  • Goto K  et al. Activation of 5-HT4 receptors facilitates neurogenesis from transplanted neural stem cells in the anastomotic ileum. J Physiol Sci 66:67-76 (2016). IHC . PubMed: 26335766
  • De la Rosa-Prieto C  et al. Neurogenesis, Neurodegeneration, Interneuron Vulnerability, and Amyloid-ß in the Olfactory Bulb of APP/PS1 Mouse Model of Alzheimer's Disease. Front Neurosci 10:227 (2016). IF . PubMed: 27303258
  • Takahashi H  et al. A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors. J Neurosci 36:8210-27 (2016). PubMed: 27488640
  • Bobylev I  et al. Toxicity to sensory neurons and Schwann cells in experimental linezolid-induced peripheral neuropathy. J Antimicrob Chemother 71:685-91 (2016). PubMed: 26612872
  • Zhang Y  et al. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nat Med 22:1160-1169 (2016). PubMed: 27571347
  • Gödde K  et al. Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination. Nat Commun 7:12043 (2016). PubMed: 27389623
  • Kaji I  et al. Luminal 5-HT stimulates colonic bicarbonate secretion in rats. Br J Pharmacol 172:4655-70 (2015). PubMed: 26061462
  • Fisher PW  et al. Increased CCN2, substance P and tissue fibrosis are associated with sensorimotor declines in a rat model of repetitive overuse injury. J Cell Commun Signal 9:37-54 (2015). PubMed: 25617052
  • Arosh JA  et al. Molecular and preclinical basis to inhibit PGE2 receptors EP2 and EP4 as a novel nonsteroidal therapy for endometriosis. Proc Natl Acad Sci U S A 112:9716-21 (2015). IHC-Fr ; Mouse . PubMed: 26199416
  • Uc A  et al. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clin Sci (Lond) 128:131-42 (2015). PubMed: 25142104
  • Beeken M  et al. Alterations in the Ubiquitin Proteasome System in Persistent but Not Reversible Proteinuric Diseases. J Am Soc Nephrol N/A:N/A (2014). PubMed: 24722446
  • Fernandes VS  et al. Hydrogen sulfide plays a key role in the inhibitory neurotransmission to the pig intravesical ureter. PLoS One 9:e113580 (2014). IHC-Fr ; Pig . PubMed: 25415381
  • Zhang X  et al. Ubiquitin Carboxyl Terminal Hydrolyase L1 -Suppressed Autophagic Degradation of p21WAF1/Cip1 as a Novel Feedback Mechanism in the Control of Cardiac Fibroblast Proliferation. PLoS One 9:e94658 (2014). WB . PubMed: 24732420
  • Bakovic M  et al. Changes in cardiac innervation during maturation in long-term diabetes. Exp Gerontol 48:1473-8 (2013). Rat . PubMed: 24140619
  • Suda K  et al. Involvement of parasympathetic pelvic efferent pathway in psychological stress-induced defecation. World J Gastroenterol 19:1200-9 (2013). PubMed: 23482518
  • Mizuguchi R  et al. Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci 32:8831-44 (2012). IHC ; Mouse . PubMed: 22745484
  • Liu J  et al. Alterations of calcium channels and cell excitability in intracardiac ganglion neurons from type 2 diabetic rats. Am J Physiol Cell Physiol 302:C1119-27 (2012). IHC . PubMed: 22189553
  • Kapuralin K  et al. Neurons and a subset of interstitial cells of Cajal in the enteric nervous system highly express Stam2 gene. Anat Rec (Hoboken) 295:113-20 (2012). PubMed: 22140097
  • Chalazonitis A  et al. Homeodomain Interacting Protein Kinase 2 Regulates Postnatal Development of Enteric Dopaminergic Neurons and Glia via BMP Signaling. J Neurosci 31:13746-57 (2011). IHC-FoFr ; Mouse . PubMed: 21957238
  • Sohn WJ  et al. Morphological evidences in circumvallate papilla and von Ebners' gland development in mice. Anat Cell Biol 44:274-83 (2011). IHC . PubMed: 22254156
  • Fedorczyk JM  et al. Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury. J Orthop Res 28:298-307 (2010). PubMed: 19743505
  • Burmeister D  et al. Early stages of in situ bladder regeneration in a rodent model. Tissue Eng Part A 16:2541-51 (2010). IHC-P ; Rat . PubMed: 20235833
  • Sogawa C  et al. Gastrointestinal tract disorder in natriuretic peptide receptor B gene mutant mice. Am J Pathol 177:822-8 (2010). IHC-P ; Mouse . PubMed: 20616347
  • Theodorou E  et al. A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. Genes Dev 23:575-88 (2009). ICC/IF ; Mouse . PubMed: 19270158
  • Ritter JM  et al. Gastric neuroendocrine carcinomas in bearded dragons (Pogona vitticeps). Vet Pathol 46:1109-16 (2009). IHC-P . PubMed: 19605903
  • Luo J  et al. Asymmetric distribution of UCH-L1 in spermatogonia is associated with maintenance and differentiation of spermatogonial stem cells. J Cell Physiol 220:460-8 (2009). PubMed: 19388011
  • García-Pascual A  et al. Interstitial cells of Cajal in the urethra are cGMP-mediated targets of nitrergic neurotransmission. Am J Physiol Renal Physiol 295:F971-83 (2008). IHC-Fr ; Sheep . PubMed: 18632793
  • Arciszewski MB  et al. Immunohistochemical localization of galanin receptors (GAL-R1, GAL-R2, and GAL-R3) on myenteric neurons from the sheep and dog stomach. Ann Anat 190:360-7 (2008). IHC-Fr ; Dog, Sheep . PubMed: 18595677
  • Chopra B  et al. Expression and function of rat urothelial P2Y receptors. Am J Physiol Renal Physiol 294:F821-9 (2008). PubMed: 18216148
  • Zhu S  et al. Immunolocalization of Periostin-like factor and Periostin during embryogenesis. J Histochem Cytochem 56:329-45 (2008). PubMed: 18040074
  • Petersen-Jones SM  et al. Ocular melanosis in the Cairn Terrier: histopathological description of the condition, and immunohistological and ultrastructural characterization of the characteristic pigment-laden cells. Vet Ophthalmol 11:260-8 (2008). IHC-P ; Dog . PubMed: 18638353
  • Pucovský V  et al. Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell. J Cell Mol Med 11:764-75 (2007). PubMed: 17760838
  • Klinger MB  et al. Expression of cyclooxygenase-2 in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol 293:R677-85 (2007). PubMed: 17537839
  • Haworth R  et al. Pulmonary neuroendocrine cell hyperplasia: identification, diagnostic criteria and incidence in untreated ageing rats of different strains. Toxicol Pathol 35:735-40 (2007). PubMed: 17849355
  • Corrow KA & Vizzard MA Phosphorylation of extracellular signal-regulated kinases in urinary bladder in rats with cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol 293:R125-34 (2007). PubMed: 17409261
  • LaBerge J  et al. Expression of corticotropin-releasing factor and CRF receptors in micturition pathways after cyclophosphamide-induced cystitis. Am J Physiol Regul Integr Comp Physiol 291:R692-703 (2006). IHC-Fr ; Mouse . PubMed: 16614059
  • Studeny S  et al. P2X2 and P2X3 receptor expression in postnatal and adult rat urinary bladder and lumbosacral spinal cord. Am J Physiol Regul Integr Comp Physiol 289:R1155-68 (2005). PubMed: 15947072
  • Yip L  et al. Role of adenosine A1 receptor in the regulation of gastrin release. J Pharmacol Exp Ther 310:477-87 (2004). PubMed: 15044554
  • Yip L & Kwok YN Role of adenosine A2A receptor in the regulation of gastric somatostatin release. J Pharmacol Exp Ther 309:804-15 (2004). PubMed: 14742743
  • Yip L  et al. Cellular localization and distribution of neurokinin-1 receptors in the rat stomach. Auton Neurosci 104:95-108 (2003). PubMed: 12648611
  • Wilson PO  et al. The immunolocalization of protein gene product 9.5 using rabbit polyclonal and mouse monoclonal antibodies. Br J Exp Pathol 69:91-104 (1988). PubMed: 2964855


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