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Cell Biology Apoptosis Receptors Associated Proteins
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Anti-PGRPS antibody (ab232728)

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  • SDS
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Immunocytochemistry/ Immunofluorescence - Anti-PGRPS antibody (ab232728)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGRPS antibody (ab232728)
  • Western blot - Anti-PGRPS antibody (ab232728)
  • Western blot - Anti-PGRPS antibody (ab232728)

Key features and details

  • Rabbit polyclonal to PGRPS
  • Suitable for: WB, ICC/IF, IHC-P
  • Reacts with: Rat, Human
  • Isotype: IgG

You may also be interested in

Protein
Product image
Recombinant Human PGRPS protein (BSA and azide free) (ab175469)
Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

View more associated products

Overview

  • Product name

    Anti-PGRPS antibody
    See all PGRPS primary antibodies
  • Description

    Rabbit polyclonal to PGRPS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment (His-T7-tag) corresponding to Rat PGRPS aa 1 to the C-terminus. Two N-terminal tags, (Expressed in E.coli).
    Database link: Q9JLN4

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • WB: Human urine; Recombinant rat PGRPS protein. IHC-P: Rat spleen tissue. ICC/IF: HeLa cells.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cell Biology
    • Apoptosis
    • Receptors
    • Associated Proteins
    • Neuroscience
    • Neurology process
    • Circadian Rhythm
    • Hormones
    • Microbiology
    • Protein
    • Human Protein
    • Defensin
    • Immunology
    • Innate Immunity
    • Cytokines
    • Other
    • Cancer
    • Cell Death
    • Apoptosis
    • Receptors
    • Associated Proteins

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human PGRPS protein (BSA and azide free) (ab175469)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab232728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Use a concentration of 0.5 - 5 µg/ml.
ICC/IF
Use a concentration of 5 - 20 µg/ml.
IHC-P
Use a concentration of 5 - 20 µg/ml.
Notes
WB
Use a concentration of 0.5 - 5 µg/ml.
ICC/IF
Use a concentration of 5 - 20 µg/ml.
IHC-P
Use a concentration of 5 - 20 µg/ml.

Target

  • Function

    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • Tissue specificity

    Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
  • Sequence similarities

    Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
  • Post-translational
    modifications

    N-glycosylated. N-glycosylation is required for bactericidal activity.
  • Cellular localization

    Secreted. Cytoplasmic granule.
  • Target information above from: UniProt accession O75594 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 8993 Human
    • Entrez Gene: 84387 Rat
    • Omim: 604963 Human
    • SwissProt: O75594 Human
    • SwissProt: Q9JLN4 Rat
    • Unigene: 137583 Human
    • Unigene: 2834 Rat
    • Alternative names

      • MGC126894 antibody
      • MGC126896 antibody
      • Peptidoglycan recognition protein 1 antibody
      • Peptidoglycan recognition protein antibody
      • Peptidoglycan recognition protein short antibody
      • PGLYRP antibody
      • PGLYRP1 antibody
      • PGRP antibody
      • PGRP S antibody
      • PGRP-S antibody
      • PGRP1_HUMAN antibody
      • PHRP, short antibody
      • SBBI68 antibody
      • TAG7 antibody
      • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) antibody
      • TNFSF 3L antibody
      • TNFSF3L antibody
      • UNQ639/PRO1269 antibody
      see all

    Images

    • Immunocytochemistry/ Immunofluorescence - Anti-PGRPS antibody (ab232728)
      Immunocytochemistry/ Immunofluorescence - Anti-PGRPS antibody (ab232728)

      Paraformaldehyde-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for PGRPS using ab232728 at 20 µg/mL in ICC/IF. FITC staining.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGRPS antibody (ab232728)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGRPS antibody (ab232728)

      Formalin-fixed, paraffin-embedded rat spleen tissue stained for PGRPS using ab232728 at 20 µg/mL in immunohistochemical analysis. DAB staining.

    • Western blot - Anti-PGRPS antibody (ab232728)
      Western blot - Anti-PGRPS antibody (ab232728)
      Anti-PGRPS antibody (ab232728) at 3 µg/ml + Human urine

      Secondary
      HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution
    • Western blot - Anti-PGRPS antibody (ab232728)
      Western blot - Anti-PGRPS antibody (ab232728)
      Anti-PGRPS antibody (ab232728) at 3 µg/ml + Recombinant rat PGRPS protein

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab232728? Please let us know so that we can cite the reference in this datasheet.

    ab232728 has not yet been referenced specifically in any publications.

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