Overview

  • Product name
    PHCCC, allosteric iator at mGlu4
  • Description
    Selective allosteric potentiator at mGlu4. Also group I antagonist.
  • Biological description
    Selective allosteric potentiator of mGlu4. Anti-Parkinson and anxiolytic effects in vivo. Also antagonist at Group I metabotropic receptors.
  • Purity
    > 98%
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Stachowicz K  et al. Anxiolytic-like effects of PHCCC, an allosteric modulator of mGlu4 receptors, in rats. Eur J Pharmacol 498:153-6 (2004). Read more (PubMed: 15363989) »
  • Marino MJ  et al. Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment. Proc Natl Acad Sci U S A 100:13668-73 (2003). Read more (PubMed: 14593202) »
See all 3 Publications for this product

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