Recombinant
RabMAb

Anti-PHD finger protein 6 antibody [EPR11996(B)] (ab170929)

Overview

  • Product name
    Anti-PHD finger protein 6 antibody [EPR11996(B)]
    See all PHD finger protein 6 primary antibodies
  • Description
    Rabbit monoclonal [EPR11996(B)] to PHD finger protein 6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human PHD finger protein 6 aa 1-100 (Cysteine residue). The exact sequence is proprietary.
    Database link: Q8IWS0

  • Positive control
    • K562, HeLa, Jurkat and 293T cell lysates, HeLa cells
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR11996(B)
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function
      May play a role in transcriptional regulation.
    • Tissue specificity
      Ubiquitously expressed.
    • Involvement in disease
      Defects in PHF6 are the cause of Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900]; also known as Boerjeson-Forssman syndrome (BORJ). BFLS is a X-linked recessive disorder characterized by moderate to severe mental retardation, epilepsy, hypogonadism, hypometabolism, obesity with marked gynecomastia, swelling of subcutaneous tissue of the face, narrow palpebral fissure and large but not deformed ears.
    • Sequence similarities
      Contains 2 PHD-type zinc fingers.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization
      Nucleus. Nucleus > nucleolus. Nuclear, it particularly localizes to the nucleolus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AC004383.6 antibody
      • BFLS antibody
      • BORJ antibody
      • CENP 31 antibody
      • Centromere protein 31 antibody
      • MGC14797 antibody
      • OTTHUMP00000024063 antibody
      • PHD finger protein 6 antibody
      • PHD like zinc finger protein antibody
      • PHD-like zinc finger protein antibody
      • Phf6 antibody
      • PHF6_HUMAN antibody
      see all

    Images

    • Immunofluorescence analysis of HeLa cells labeling PHD finger protein 6 with ab170929 at 1/100 dilution.

    • All lanes : Anti-PHD finger protein 6 antibody [EPR11996(B)] (ab170929) at 1/1000 dilution

      Lane 1 : K562 cell lysates
      Lane 2 : HeLa cell lysates
      Lane 3 : Jurkat cell lysates
      Lane 4 : 293T cell lysates

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 41 kDa

    References

    ab170929 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab170929.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up