Product namePhenazopyridine hydrochloride, local analgesic
DescriptionLocal analgesic used in urinary tract disorders
- 2,6-Diamino-3-(phenylazo)pyridine hydrochloride
- Phenazopyridine HCl
Excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. Directly inhibits the mechanosensitive Aδ-fibers in the normal rat bladder. Induces and synchronizes neuronal differentiation of embryonic stem cells.
Chemical name3-[(1E)-2-Phenyldiazenyl]-2,6-pyridinediamine hydrochloride
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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This product has been referenced in:
- Aizawa N & Wyndaele JJ Effects of phenazopyridine on rat bladder primary afferent activity, and comparison with lidocaine and acetaminophen. Neurourol Urodyn 29:1445-50 (2010). Read more (PubMed: 20976818) »
- Suter DM et al. Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells. J Cell Mol Med 13:3517-27 (2009). Read more (PubMed: 20196783) »
- Gaines KK Phenazopyridine hydrochloride: the use and abuse of an old standby for UTI. Urol Nurs 24:207-9 (2004). Read more (PubMed: 15311491) »