Phenazopyridine hydrochloride, local analgesic (ab145808)

Overview

  • Product name

    Phenazopyridine hydrochloride, local analgesic
  • Description

    Local analgesic used in urinary tract disorders
  • Alternative names

    • 2,6-Diamino-3-(phenylazo)pyridine hydrochloride
    • Phenazopyridine HCl
    • Pyridium
    • Urodine
  • Biological description

    Excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. Directly inhibits the mechanosensitive Aδ-fibers in the normal rat bladder. Induces and synchronizes neuronal differentiation of embryonic stem cells.

  • Purity

    > 99%
  • CAS Number

    136-40-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-[(1E)-2-Phenyldiazenyl]-2,6-pyridinediamine hydrochloride
  • Molecular weight

    249.70
  • Molecular formula

    C11H11N5.HCl
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Aizawa N & Wyndaele JJ Effects of phenazopyridine on rat bladder primary afferent activity, and comparison with lidocaine and acetaminophen. Neurourol Urodyn 29:1445-50 (2010). Read more (PubMed: 20976818) »
  • Suter DM  et al. Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells. J Cell Mol Med 13:3517-27 (2009). Read more (PubMed: 20196783) »
  • Gaines KK Phenazopyridine hydrochloride: the use and abuse of an old standby for UTI. Urol Nurs 24:207-9 (2004). Read more (PubMed: 15311491) »

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