Overview

  • Product name

    Phenelzine sulfate, MAO inhibitor
  • Description

    Non-selective, irreversible MAO inhibitor
  • Biological description

    Non-selective, irreversible MAO inhibitor. Inhibits the 5-HT inward current (IC50 = 1.3 μM). Increases GABA concentrations. Shows antidepressant and anxiolytic effects in vivo. Orally active.
  • CAS Number

    156-51-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Byun Y  et al. The opposite effect of isotype-selective monoamine oxidase inhibitors on adipogenesis in human bone marrow mesenchymal stem cells. Bioorg Med Chem Lett 23:3273-6 (2013). Read more (PubMed: 23611731) »
  • Benson CA  et al. The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE). Behav Brain Res 252:302-11 (2013). Read more (PubMed: 23777648) »
  • Fan P Effects of antidepressants on the inward current mediated by 5-HT3 receptors in rat nodose ganglion neurones. Br J Pharmacol 112:741-4 (1994). Read more (PubMed: 7522857) »

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