Phenelzine sulfate, MAO inhibitor (ab144825)
- Datasheet
- References
Overview
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Product name
Phenelzine sulfate, MAO inhibitor -
Description
Non-selective, irreversible MAO inhibitor -
Biological description
Non-selective, irreversible MAO inhibitor. Inhibits the 5-HT inward current (IC50 = 1.3 μM). Increases GABA concentrations. Shows antidepressant and anxiolytic effects in vivo. Orally active. -
CAS Number
156-51-4 -
Chemical structure
Properties
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Chemical name
2-Phenylethylhydrazine sulfate -
Molecular weight
234.27 -
Molecular formula
C8H12N2.H2SO4 -
PubChem identifier
61100 -
Storage instructions
Store at +4°C (desiccating conditions). -
Solubility overview
Soluble in water to 100 mM -
Handling
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CC=C(C=C1)CCNN.OS(=O)(=O)O -
Source
Synthetic
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Research areas
References
This product has been referenced in:
- Byun Y et al. The opposite effect of isotype-selective monoamine oxidase inhibitors on adipogenesis in human bone marrow mesenchymal stem cells. Bioorg Med Chem Lett 23:3273-6 (2013). Read more (PubMed: 23611731) »
- Benson CA et al. The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE). Behav Brain Res 252:302-11 (2013). Read more (PubMed: 23777648) »
- Fan P Effects of antidepressants on the inward current mediated by 5-HT3 receptors in rat nodose ganglion neurones. Br J Pharmacol 112:741-4 (1994). Read more (PubMed: 7522857) »
