Phenylethyl 3-methylcaffeate (PEMC), chemopreventive agent (ab143680)

Overview

  • Product name

    Phenylethyl 3-methylcaffeate (PEMC), chemopreventive agent
  • Description

    Chemopreventive agent. Lipoxygenase, tyrosine protein kinase and ornithine decarboxylase inhibitor.
  • Alternative names

    • PEMC
  • Biological description

    Chemopreventive agent. Lipoxygenase, tyrosine protein kinase and ornithine decarboxylase inhibitor. Caffeic acid (ab120862) ester. Induces apoptosis. Prevents carcinogen-induced aberrant foci formation. Shows chemopreventive and antitumor effects in vivo. Orally active.
  • Purity

    > 97%
  • CAS Number

    71835-85-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Samaha HS  et al. Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion. Cancer Res 57:1301-5 (1997). Read more (PubMed: 9102217) »
  • Rao CV  et al. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res 55:2310-5 (1995). Read more (PubMed: 7757981) »
  • Rao CV  et al. Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon. Cancer Res 53:4182-8 (1993). Read more (PubMed: 8364913) »

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