Philanthotoxin-7,4 (PhTx-74) (mM/ml), GluA1/GluA2 (formerly GluR1/2) inhibitor (ab146706)

Overview

  • Product name

    Philanthotoxin-7,4 (PhTx-74) (mM/ml), GluA1/GluA2 (formerly GluR1/2) inhibitor
  • Description

    GluA1/GluA2 (formerly GluR1/2) inhibitor. 1 ml water soluble pack.
  • Alternative names

    • PhTx-74
  • Biological description

    A subtype-selective, use-dependent inhibitor of native AMPA receptors. Inhibits GluA1/A2 (formerly GluR1/2), with little activity at GluA2/A3 (formerly GluR2/3)

    Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
  • Purity

    > 98%
  • CAS Number

    401601-12-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (S)-N-[7-[(4-Aminobutyl)amino]heptyl]-4-hydroxy-a-[(1-oxobutyl)amino]benzenepropanamide dihydrochloride
  • Molecular weight

    507.54
  • Molecular formula

    C24H42N4O3.2HCl
  • PubChem identifier

    46213501
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in 1ml of water to give specified mM/ml concentration
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.Cl.Oc1ccc(C[C@H](NC(=O)CCC)C(=O)NCCCCCCCNCCCCN)cc1
  • Source

    Synthetic

  • Research areas

References

ab146706 has not yet been referenced specifically in any publications.

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