Anti-Phospholamban antibody [2D12] (ab2865)

Mouse monoclonal Phospholamban antibody [2D12]. Validated in WB, IP, IHC, Inhibition, ICC/IF and tested in Mouse, Rat, Sheep, Rabbit, Chicken, Guinea pig, Dog, Human, Pig. Cited in 34 publication(s).

Publishing research using ab2865? Please let us know so that we can cite the reference in this datasheet.

ab2865 has been referenced in 34 publications.

  • Meraviglia V  et al. HDAC Inhibition Improves the Sarcoendoplasmic Reticulum Ca2+-ATPase Activity in Cardiac Myocytes. Int J Mol Sci 19:N/A (2018). PubMed: 29385061
  • Christiansen D  et al. Increased FXYD1 and PGC-1a mRNA after blood flow-restricted running is related to fibre type-specific AMPK signalling and oxidative stress in human muscle. Acta Physiol (Oxf) 223:e13045 (2018). PubMed: 29383885
  • Olivares-Florez S  et al. Nuclear calcineurin is a sensor for detecting Ca2+ release from the nuclear envelope via IP3R. J Mol Med (Berl) 96:1239-1249 (2018). PubMed: 30293136
  • Savi M  et al. In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats. Cardiovasc Diabetol 16:80 (2017). PubMed: 28683791
  • Aston D  et al. High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart. Sci Rep 7:40620 (2017). PubMed: 28094777
  • Hu LR  et al. Deregulated Ca(2+) cycling underlies the development of arrhythmia and heart disease due to mutant obscurin. Sci Adv 3:e1603081 (2017). WB, IF ; Mouse . PubMed: 28630914
  • Wu Y  et al. Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation. Biomed Res Int 2017:4150158 (2017). PubMed: 28536695
  • Wang Y  et al. The Involvement of Ca(2+) Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis. Chin Med J (Engl) 129:1185-92 (2016). WB . PubMed: 27174327
  • Zaman JA  et al. Post-operative atrial fibrillation is associated with a pre-existing structural and electrical substrate in human right atrial myocardium. Int J Cardiol 220:580-8 (2016). PubMed: 27390994
  • Te Rijdt WP  et al. Phospholamban p.Arg14del cardiomyopathy is characterized by phospholamban aggregates, aggresomes, and autophagic degradation. Histopathology 69:542-50 (2016). PubMed: 26970417
  • Ahmad F  et al. Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2. J Biol Chem 290:6763-76 (2015). PubMed: 25593322
  • Castillero E  et al. Attenuation of the unfolded protein response and endoplasmic reticulum stress after mechanical unloading in dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 309:H459-70 (2015). WB ; Human . PubMed: 26055788
  • Chen G  et al. Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circ Arrhythm Electrophysiol 8:193-202 (2015). PubMed: 25504561
  • Little SC  et al. Protein phosphatase 2A regulatory subunit B56a limits phosphatase activity in the heart. Sci Signal 8:ra72 (2015). PubMed: 26198358
  • Tang Y  et al. Nitric oxide enhances extracellular ATP induced Ca²? oscillation in HeLa cells. Arch Biochem Biophys 565:68-75 (2015). PubMed: 25461674
  • Curran J  et al. EHD3-dependent endosome pathway regulates cardiac membrane excitability and physiology. Circ Res 115:68-78 (2014). PubMed: 24759929
  • Wang W  et al. Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance. Nat Med 19:305-12 (2013). WB . PubMed: 23396207
  • Turdi S  et al. Tauroursodeoxycholic acid mitigates high fat diet-induced cardiomyocyte contractile and intracellular Ca2+ anomalies. PLoS One 8:e63615 (2013). WB ; Mouse . PubMed: 23667647
  • Roe ND  et al. Folic acid reverses nitric oxide synthase uncoupling and prevents cardiac dysfunction in insulin resistance: role of Ca2+/calmodulin-activated protein kinase II. Free Radic Biol Med 65:234-43 (2013). WB ; Mouse . PubMed: 23820268
  • Ceholski DK  et al. Hydrophobic imbalance in the cytoplasmic domain of phospholamban is a determinant for lethal dilated cardiomyopathy. J Biol Chem 287:16521-9 (2012). WB . PubMed: 22427649
  • Miyazaki Y  et al. Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling. PLoS One 7:e35875 (2012). Mouse . PubMed: 22558250
  • Moon MR  et al. Differential calcium handling in two canine models of right ventricular pressure overload. J Surg Res 178:554-62 (2012). PubMed: 22632938
  • Smeazzetto S  et al. Phospholamban generates cation selective ion channels. Phys Chem Chem Phys 13:12935-9 (2011). Functional Studies . PubMed: 21687864
  • Aoyama H  et al. Isoform-specific roles of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated Ca(2+) cycling. Cardiovasc Res 89:79-88 (2011). PubMed: 20675715
  • Wang YY  et al. Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy. Cardiovasc Res 87:636-46 (2010). WB ; Mouse . PubMed: 20453157
  • Patel HH  et al. Disruption of Protein Kinase A Localization Using a Trans-activator of Transcription (TAT)-conjugated A-kinase-anchoring Peptide Reduces Cardiac Function. J Biol Chem 285:27632-40 (2010). WB ; Rat . PubMed: 20581396
  • McCormick C  et al. Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism. J Appl Physiol (1985) 109:1716-27 (2010). PubMed: 20864554
  • Zhan DY  et al. Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation. Cardiovasc Res 84:64-71 (2009). PubMed: 19477965
  • Turdi S  et al. Acute methamphetamine exposure inhibits cardiac contractile function. Toxicol Lett 189:152-8 (2009). WB ; Mouse . PubMed: 19481142
  • Jessup JA  et al. Dual ACE-inhibition and AT1 receptor antagonism improves ventricular lusitropy without affecting cardiac fibrosis in the congenic mRen2.Lewis rat. Ther Adv Cardiovasc Dis 3:245-57 (2009). PubMed: 19531557
  • Day SM  et al. Cardiac-directed parvalbumin transgene expression in mice shows marked heart rate dependence of delayed Ca2+ buffering action. Physiol Genomics 33:312-22 (2008). PubMed: 18334547
  • García-Pérez C  et al. Physical coupling supports the local Ca2+ transfer between sarcoplasmic reticulum subdomains and the mitochondria in heart muscle. J Biol Chem 283:32771-80 (2008). PubMed: 18790739
  • Butler J  et al. Phospholamban and sarcolipin are maintained in the endoplasmic reticulum by retrieval from the ER-Golgi intermediate compartment. Cardiovasc Res 74:114-23 (2007). PubMed: 17307155
  • Ranasinghe AM  et al. How does glucose insulin potassium improve hemodynamic performance? Evidence for altered expression of beta-adrenoreceptor and calcium handling genes. Circulation 114:I239-44 (2006). WB ; Human . PubMed: 16820579


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