Overview

  • Product name

    Anti-Phospholipase A2 XII/PLA2G12A antibody [7C7C9]
    See all Phospholipase A2 XII/PLA2G12A primary antibodies
  • Description

    Mouse monoclonal [7C7C9] to Phospholipase A2 XII/PLA2G12A
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, Flow Cytmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant full length protein corresponding to Human Phospholipase A2 XII/PLA2G12A aa 21-189. Recombinant full length mature expressed in E coli
    Sequence:

    RCQEQAQTTD WRATLKTIRN GVHKIDTYLN AALDLLGGED GLCQYKCSDG SKPFPRYGYK PSPPNGCGSP LFGVHLNIGI PSLTKCCNQH DRCYETCGKS KNDCDEEFQY CLSKICRDVQ KTLGLTQHVQ ACETTVELLF DSVIHLGCKP YLDSQRAACR CHYEEKTDL


    Database link: Q9BZM1

  • Positive control

    • Human Phospholipase A2 XII/PLA2G12A (AA: 21-189) recombinant protein; Phospholipase A2 XII/PLA2G12A (AA: 21-189)-hIgGFc transfected HEK293 cell lysate and HeLa cells.
  • General notes

     This product was previously labelled as Phospholipase A2 XII

     

Properties

Applications

Our Abpromise guarantee covers the use of ab201950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 21 kDa.
Flow Cyt 1/200 - 1/400.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
  • Tissue specificity

    Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
  • Sequence similarities

    Belongs to the phospholipase A2 family.
  • Cellular localization

    Secreted. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 3.1.1.4 antibody
    • Group XII secreted phospholipase A2 antibody
    • Group XIIA secreted phospholipase A2 antibody
    • Group XIIA secretory phospholipase A2 antibody
    • Group XIIA secretory phospholipase A2 precursor antibody
    • GXII antibody
    • GXII sPLA2 antibody
    • PG12A_HUMAN antibody
    • phosphatidylcholine 2 acylhydrolase 12A antibody
    • Phosphatidylcholine 2 acylhydrolase GXII antibody
    • Phosphatidylcholine 2-acylhydrolase 12A antibody
    • Phospholipase A2 group XIIA antibody
    • PLA2G12 antibody
    • Pla2g12a antibody
    • ROSSY antibody
    • sPLA2 XII antibody
    • sPLA2-XII antibody
    see all

Images

  • Flow cytometric analysis of HeLa cells labeling Phospholipase A2 XII/PLA2G12A  (green) using ab201950 at 1/200 dilution and negative control (red).

  • All lanes : Anti-Phospholipase A2 XII/PLA2G12A antibody [7C7C9] (ab201950) at 1/500 dilution

    Lane 1 : HEK293 cell lysate
    Lane 2 : Phospholipase A2 XII/PLA2G12A (AA: 21-189)-hIgGFc transfected HEK293 cell lysate

    Predicted band size: 21 kDa

  • Anti-Phospholipase A2 XII/PLA2G12A antibody [7C7C9] (ab201950) at 1/500 dilution + Human Phospholipase A2 XII/PLA2G12A (AA: 21-189) recombinant protein.

    Predicted band size: 21 kDa

References

ab201950 has not yet been referenced specifically in any publications.

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