Overview

  • Product name

    Anti-Phospholipase A2 XII/PLA2G12A antibody
    See all Phospholipase A2 XII/PLA2G12A primary antibodies
  • Description

    Rabbit polyclonal to Phospholipase A2 XII/PLA2G12A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human Phospholipase A2 XII/PLA2G12A (internal sequence). The exact sequence is proprietary.
    Database link: Q9BZM1

  • Positive control

    • IHC-P: Human colon carcinoma tissue. WB: HeLa whole cell lysate.
  • General notes

     This product was previously labelled as Phospholipase A2 XII

     

Properties

Applications

Our Abpromise guarantee covers the use of ab227477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 21 kDa.

Target

  • Function

    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
  • Tissue specificity

    Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
  • Sequence similarities

    Belongs to the phospholipase A2 family.
  • Cellular localization

    Secreted. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • EC 3.1.1.4 antibody
    • Group XII secreted phospholipase A2 antibody
    • Group XIIA secreted phospholipase A2 antibody
    • Group XIIA secretory phospholipase A2 antibody
    • Group XIIA secretory phospholipase A2 precursor antibody
    • GXII antibody
    • GXII sPLA2 antibody
    • PG12A_HUMAN antibody
    • phosphatidylcholine 2 acylhydrolase 12A antibody
    • Phosphatidylcholine 2 acylhydrolase GXII antibody
    • Phosphatidylcholine 2-acylhydrolase 12A antibody
    • Phospholipase A2 group XIIA antibody
    • PLA2G12 antibody
    • Pla2g12a antibody
    • ROSSY antibody
    • sPLA2 XII antibody
    • sPLA2-XII antibody
    see all

Images

  • Paraffin-embedded human colon carcinoma tissue stained for Phospholipase A2 XII/PLA2G12A using ab227477 at 1/500 dilution in immunohistochemical analysis.

  • Anti-Phospholipase A2 XII/PLA2G12A antibody (ab227477) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 21 kDa



    12% SDS-PAGE gel.

References

ab227477 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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