Overview

  • Product name
    Anti-Phospholipase C gamma 1 + 2 antibody
  • Description
    Rabbit polyclonal to Phospholipase C gamma 1 + 2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Phospholipase C gamma 1 + 2. It surrounds amino acid 1252 of Phospholipase C gamma 2.
    Database link: P16885

  • Positive control
    • Jurkat cell lysate, Human brain cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab174787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 148 kDa.

It should be user determined

Target

  • Relevance
    PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCß, PLCg, PLCd, and PLCe. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCg2 is engaged in antigen dependent signaling in B-cells and collagen-dependent signaling in platelets.
  • Cellular localization
    Cytoplasmic and Plasma membrane
  • Database links
  • Alternative names
    • 1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase gamma 1 antibody
    • 1 phosphatidylinositol 4,5 bisphosphate phosphodiesterase gamma 2 antibody
    • 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate antibody
    • AI894140 antibody
    • APLAID antibody
    • Cded antibody
    • EC 3.1.4.11 antibody
    • FCAS3 antibody
    • fj46f04 antibody
    • fj57a05 antibody
    • inositoltrisphosphohydrolase antibody
    • MGC38590 antibody
    • monophosphatidylinositol phosphodiesterase antibody
    • NCKAP3 antibody
    • phosphatidylinositol phospholipase C antibody
    • phosphoinositidase C antibody
    • Phosphoinositide phospholipase C antibody
    • phosphoinositide phospholipase C-gamma-1 antibody
    • phosphoinositide phospholipase C-gamma-2 antibody
    • phospholipase C, gamma 1 (formerly subtype 148) antibody
    • phospholipase C, gamma 1 antibody
    • phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody
    • phospholipase C, gamma 2 antibody
    • phospholipase C, phosphatidylinositol-specific antibody
    • phospholipase C-148 antibody
    • phospholipase C-II antibody
    • phospholipase C-IV antibody
    • Plc 1 antibody
    • Plc gamma1 antibody
    • PLC II antibody
    • PLC IV antibody
    • PLC-gamma-2 antibody
    • PLC1 antibody
    • PLC148 antibody
    • Plcg 1 antibody
    • Plcg 2 antibody
    • PLCG1 antibody
    • PLCG2 antibody
    • PLCgamma1 antibody
    • PPLCA antibody
    • triphosphoinositide phosphodiesterase antibody
    • wu:fj46f04 antibody
    • wu:fj57a05 antibody
    see all

Images

  • Anti-Phospholipase C gamma 1 + 2 antibody (ab174787) + Jurkat cell lysate

    Predicted band size: 148 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, cortex, tissue, labeling Phospholipase C gamma 1 + 2 using ab174787 at 5 µg/ml.

References

ab174787 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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