Product nameAnti-Phosphorylase B/PHKB antibody
See all Phosphorylase B/PHKB primary antibodies
DescriptionSheep polyclonal to Phosphorylase B/PHKB
Recognizes Phosphorylase B/PHKB. Exhibits high crossreactivity (95-135%) with Phosphorylase A by ELISA.
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Rabbit
Full length native protein (purified) corresponding to Rabbit Phosphorylase B/PHKB.
This product was previously labelled as Phosphorylase B
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: Whole serum
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab31121 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||1/300 - 1/1000.|
|WB||1/500 - 1/1000. Predicted molecular weight: 121 kDa.|
FunctionPhosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
PathwayGlycan biosynthesis; glycogen metabolism.
Involvement in diseaseGlycogen storage disease 9B
Sequence similaritiesBelongs to the phosphorylase b kinase regulatory chain family.
modificationsSer-701 is probably phosphorylated by PKA.
Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
Cellular localizationCell membrane.
- Information by UniProt
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ab31121 has not yet been referenced specifically in any publications.