Key features and details
- Rabbit polyclonal to Phosphoserine Aminotransferase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Phosphoserine Aminotransferase antibody
See all Phosphoserine Aminotransferase primary antibodies
DescriptionRabbit polyclonal to Phosphoserine Aminotransferase
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit
Recombinant fragment corresponding to Human Phosphoserine Aminotransferase aa 138-340. (BC000971).
STWNLNPDASYVYYCANETVHGVEFDFIPDVKGAVLVCDMSSNFLSKPVD VSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNS SLYNTPPCFSIYVMGLVLEWIKNNGGAAAMEKLSSIKSQTIYEIIDNSQG FYVCPVEPQNRSKMNIPFRIGNAKGDDALEKRFLDKALELNMLSLKGHRS VGG
Database link: Q9Y617
- Human fetal brain lysate; Human fetal kidney tissue.
FormLyophilized:Reconstitute in 200 ul of sterile distilled water.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197185 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/1000. Predicted molecular weight: 40 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionCatalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Tissue specificityExpressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
PathwayAmino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.
Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.
Involvement in diseaseDefects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD) [MIM:610992]. PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation.
Sequence similaritiesBelongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
- Information by UniProt
- EC 184.108.40.206 antibody
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ab197185 has not yet been referenced specifically in any publications.