Anti-PI 3 Kinase catalytic subunit gamma/PI3K-gamma antibody [OTI4H9] (ab139307)

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Overview

  • Product name

    Anti-PI 3 Kinase catalytic subunit gamma/PI3K-gamma antibody [OTI4H9]
    See all PI 3 Kinase catalytic subunit gamma/PI3K-gamma primary antibodies

  • Description

    Mouse monoclonal [OTI4H9] to PI 3 Kinase catalytic subunit gamma/PI3K-gamma

  • Host species

    Mouse

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Pig

  • Immunogen

    Recombinant full length protein corresponding to Human PI 3 Kinase catalytic subunit gamma/PI3K-gamma aa 1-1102. Produced in HEK293T cells (NP_002640).
    Sequence:

    MELENYKQPVVLREDNCRRRRRMKPRSAAASLSSMELIPIEFVLPTSQRK CKSPETALLHVAGHGNVEQMKAQVWLRALETSVAADFYHRLGPHHFLLLY QKKGQWYEIYDKYQVVQTLDCLRYWKATHRSPGQIHLVQRHPPSEESQAF QRQLTALIGYDVTDVSNVHDDELEFTRRGLVTPRMAEVASRDPKLYAMHP WVTSKPLPEYLWKKIANNCIFIVIHRSTTSQTIKVSPDDTPGAILQSFFT KMAKKKSLMDIPESQSEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG EEIHVVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVF TVSLWDCDRKFRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTS PKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIYCGKAPALSSKASAESP SSESKGKVQLLYYVNLLLIDHRFLLRRGEYVLHMWQISGKGEDQGSFNAD KLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEGDRVRAEMPNQ LRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLES LEDDDVLHYLLQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLR SEIAQSRHYQQRFAVILEAYLRGCGTAMLHDFTQQVQVIEMLQKVTLDIK SLSAEKYDVSSQVISQLKQKLENLQNSQLPESFRVPYDPGLKAGALAIEK CKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRI MESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG AFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHND NIMITETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGK KTSPHFQKFQDICVKAYLALRHHTNLLIILFSMMLMTGMPQLTSKEDIEY IRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKH SA


    Database link: P48736

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • WB: HEK-293T cell lysate transfected with PI 3 Kinase catalytic subunit gamma/PI3K-gamma cDNA.

  • General notes

    Clone OTI4H9 (formerly 4H9).

    Previously labelled as PI 3 Kinase catalytic subunit gamma. 

Properties

Applications

Our Abpromise guarantee covers the use of ab139307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 126 kDa.

Target

  • Function

    3-phosphorylates the cellular phosphoinositide PtdIns-4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5-triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production.

  • Tissue specificity

    Pancreas, skeletal muscle, liver and heart.

  • Pathway

    Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.

  • Sequence similarities

    Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • 1 phosphatidylinositol 3 kinase antibody
    • 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma antibody
    • 5-bisphosphate 3-kinase catalytic subunit gamma isoform antibody
    • p110 gamma antibody
    • p110gamma antibody
    • p120 PI3K antibody
    • p120-PI3K antibody
    • Phosphatidylinositol 3 kinase catalytic 110 kD gamma antibody
    • Phosphatidylinositol 3 kinase gamma, p110 gamma antibody
    • Phosphatidylinositol 3 kinase, catalytic, gamma polypeptide antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit gamma antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma isoform antibody
    • Phosphatidylinositol-4 antibody
    • Phosphoinositide 3 kinase catalytic gamma polypeptide antibody
    • Phosphoinositide 3 kinase gamma catalytic subunit antibody
    • PI 3 Kinase catalytic subunit gamma antibody
    • PI3 kinase p110 subunit gamma antibody
    • PI3-kinase subunit gamma antibody
    • PI3CG antibody
    • PI3K antibody
    • PI3K-gamma antibody
    • PI3Kgamma antibody
    • PIK3 antibody
    • Pik3cg antibody
    • PK3CG_HUMAN antibody
    • PtdIns-3-kinase subunit gamma antibody
    • PtdIns-3-kinase subunit p110-gamma antibody
    • Serine/threonine protein kinase PIK3CG antibody
    see all

Images

  • Western blot - Anti-PI 3 Kinase catalytic subunit gamma/PI3K-gamma antibody [OTI4H9] (ab139307)
    Western blot - Anti-PI 3 Kinase catalytic subunit gamma/PI3K-gamma antibody [OTI4H9] (ab139307)
    All lanes : Anti-PI 3 Kinase catalytic subunit gamma/PI3K-gamma antibody [OTI4H9] (ab139307) at 1/1000 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK-293T cell lysate transfected with pCMV6-ENTRY PI 3 Kinase catalytic subunit gamma/PI3K-gamma cDNA

    Lysates/proteins at 5 µg per lane.

    Predicted band size: 126 kDa

References

ab139307 has not yet been referenced specifically in any publications.

Publishing research using ab139307? Please let us know so that we can cite the reference in this datasheet.

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