Overview

  • Product name

    Anti-PI 3 Kinase p110 delta antibody
    See all PI 3 Kinase p110 delta primary antibodies
  • Description

    Rabbit polyclonal to PI 3 Kinase p110 delta
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human PI 3 Kinase p110 delta (internal sequence). The exact sequence is proprietary. Gene Accession: NP_005017
    Database link: O00329

  • Positive control

    • IHC-P: Human breast cancer tissue and Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab200372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Tissue specificity

    Expressed predominantly in leukocytes.
  • Pathway

    Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
  • Sequence similarities

    Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Post-translational
    modifications

    Autophosphorylation on Ser-1039 results in the almost complete inactivation of the lipid kinase activity.
  • Information by UniProt
  • Database links

  • Alternative names

    • 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta antibody
    • 5-bisphosphate 3-kinase catalytic subunit delta isoform antibody
    • APDS antibody
    • GRB1 antibody
    • IMD14 antibody
    • p110d antibody
    • p110delta antibody
    • p110dp85a antibody
    • p85-ALPHA antibody
    • Phosphatidylinositol 3 kinase catalytic delta polypeptide antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform antibody
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta antibody
    • Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta antibody
    • Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform antibody
    • Phosphatidylinositol-4 antibody
    • Phosphoinositide 3 kinase B antibody
    • Phosphoinositide 3 kinase C antibody
    • Phosphoinositide 3 kinase catalytic delta polypeptide antibody
    • Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta antibody
    • PI3 kinase p110 subunit delta antibody
    • PI3-kinase subunit delta antibody
    • PI3K antibody
    • PI3K-delta antibody
    • PI3Kdelta antibody
    • Pik3cd antibody
    • PIK3R1 antibody
    • PK3CD antibody
    • PK3CD_HUMAN antibody
    • PtdIns 3 kinase p110 antibody
    • PtdIns 3 kinase subunit p110 delta antibody
    • PtdIns-3-kinase subunit delta antibody
    • PtdIns-3-kinase subunit p110-delta antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling PI 3 Kinase p110 delta with ab200372 at 1/20 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling PI 3 Kinase p110 delta with ab200372 at 1/20 dilution.

References

This product has been referenced in:

  • Goulielmaki E  et al. Pharmacological inactivation of the PI3K p110d prevents breast tumour progression by targeting cancer cells and macrophages. Cell Death Dis 9:678 (2018). Read more (PubMed: 29880805) »
See 1 Publication for this product

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