Anti-PI 3 Kinase p55 gamma antibody (ab97862)
Key features and details
- Rabbit polyclonal to PI 3 Kinase p55 gamma
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PI 3 Kinase p55 gamma antibody
See all PI 3 Kinase p55 gamma primary antibodies -
Description
Rabbit polyclonal to PI 3 Kinase p55 gamma -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment, corresponding to a sequence within amino acids 242-437 of Human PI 3 Kinase p55 gamma (AAH21622).
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Positive control
- 293T, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lysates; A431 whole cell lysate. SAS xenograft tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/500.
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WB |
1/500 - 1/3000. Predicted molecular weight: 54 kDa.
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Notes |
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IHC-P
1/100 - 1/500. |
WB
1/500 - 1/3000. Predicted molecular weight: 54 kDa. |
Target
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Function
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. -
Tissue specificity
Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. -
Sequence similarities
Belongs to the PI3K p85 subunit family.
Contains 2 SH2 domains. - Information by UniProt
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Database links
- Entrez Gene: 286865 Cow
- Entrez Gene: 8503 Human
- Entrez Gene: 18710 Mouse
- Entrez Gene: 60664 Rat
- Omim: 606076 Human
- SwissProt: O46404 Cow
- SwissProt: Q92569 Human
- SwissProt: Q64143 Mouse
see all -
Alternative names
- DKFZp686P05226 antibody
- FLJ41892 antibody
- OTTHUMP00000009783 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab97862 has been referenced in 3 publications.
- Xu H et al. CircRNA_0000392 promotes colorectal cancer progression through the miR-193a-5p/PIK3R3/AKT axis. J Exp Clin Cancer Res 39:283 (2020). PubMed: 33317596
- Peng YP et al. PIK3R3 Promotes Metastasis of Pancreatic Cancer via ZEB1 Induced Epithelial-Mesenchymal Transition. Cell Physiol Biochem 46:1930-1938 (2018). PubMed: 29719293
- Mei Q et al. Genetic and Methylation-Induced Loss of miR-181a2/181b2 within chr9q33.3 Facilitates Tumor Growth of Cervical Cancer through the PIK3R3/Akt/FoxO Signaling Pathway. Clin Cancer Res 23:575-586 (2017). PubMed: 27503199