Key features and details
- Rabbit polyclonal to PI 3 Kinase p55 gamma
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PI 3 Kinase p55 gamma antibody
See all PI 3 Kinase p55 gamma primary antibodies
DescriptionRabbit polyclonal to PI 3 Kinase p55 gamma
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment, corresponding to a sequence within amino acids 242-437 of Human PI 3 Kinase p55 gamma (AAH21622).
- 293T, H1299, HeLaS3, HepG2, MOLT4 and Raji cell lysates; A431 whole cell lysate. SAS xenograft tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab97862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
|WB||1/500 - 1/3000. Predicted molecular weight: 54 kDa.|
FunctionBinds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Tissue specificityHighest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
Sequence similaritiesBelongs to the PI3K p85 subunit family.
Contains 2 SH2 domains.
- Information by UniProt
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ab97862 has been referenced in 2 publications.
- Peng YP et al. PIK3R3 Promotes Metastasis of Pancreatic Cancer via ZEB1 Induced Epithelial-Mesenchymal Transition. Cell Physiol Biochem 46:1930-1938 (2018). PubMed: 29719293
- Mei Q et al. Genetic and Methylation-Induced Loss of miR-181a2/181b2 within chr9q33.3 Facilitates Tumor Growth of Cervical Cancer through the PIK3R3/Akt/FoxO Signaling Pathway. Clin Cancer Res 23:575-586 (2017). PubMed: 27503199