Overview

  • Product name

    Anti-PI-9 antibody [PI9-17]
    See all PI-9 primary antibodies
  • Description

    Mouse monoclonal [PI9-17] to PI-9
  • Host species

    Mouse
  • Specificity

    Ab36624 recognises Proteinase Inhibitor 9, as well as Proteinase Inhibitor 9 complexed to granzyme B. It shows no cross reactivity with other homologous serpins (PI6, PI8 and PAI2) was observed.
  • Tested applications

    Suitable for: IHC-P, WBmore details
    Unsuitable for: Flow Cyt
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human PI-9.

  • Positive control

    • WB: YT-Indy cells (a natural killer leukemia cell line).

Properties

Applications

Our Abpromise guarantee covers the use of ab36624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notes
    IHC-P: 1/100. Recommeneded pretreatment with 10 mM citric acid pH 6.0 for 20 min. For fixed cytospin preparations fix cells for 10 min in 10% formalin and then treat them as paraffin sections.

    WB: Use at an assay dependent dilution. Detects a band of approximately 42, 67 kDa.

    Is unsuitable for Flow Cyt.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Granzyme B inhibitor.
    • Sequence similarities

      Belongs to the serpin family. Ov-serpin subfamily.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • CAP 3 antibody
      • CAP-3 antibody
      • CAP3 antibody
      • Cytoplasmic antiproteinase 3 antibody
      • Peptidase inhibitor 9 antibody
      • PI-9 antibody
      • PI9 antibody
      • Protease inhibitor 9 antibody
      • Protease inhibitor 9 (ovalbumin type) antibody
      • Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 9 antibody
      • Serpin B9 antibody
      • Serpin peptidase inhibitor clade B (ovalbumin) member 9 antibody
      • Serpin peptidase inhibitor clade B member 9 antibody
      • SERPINB9 antibody
      • SPB9_HUMAN antibody
      see all

    References

    This product has been referenced in:

    • El Haddad N  et al. The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cells. J Immunol 187:2252-60 (2011). Human . Read more (PubMed: 21795594) »
    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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