Product nameAnti-PICK1 antibody [EPR4130(3)]
See all PICK1 primary antibodies
DescriptionRabbit monoclonal [EPR4130(3)] to PICK1
Tested applicationsSuitable for: WB, IPmore details
Unsuitable for: Flow Cyt,ICC or IHC-P
Species reactivityReacts with: Human
A synthetic peptide corresponding to residues in Human PICK1 (UniProt ID: Q9NRD5)
- WB: Human fetal brain and LnCaP lysates
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (KD)KD = 5.30 x 10 -11 M Learn more about KD
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab133773 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 46 kDa).|
|IP||1/10 - 1/100.|
FunctionProbable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate heteromeric ACCN3/ACCN2 channel.
Sequence similaritiesContains 1 AH domain.
Contains 1 PDZ (DHR) domain.
modificationsPhosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors.
Cellular localizationCytoplasm > perinuclear region. Cell junction > synapse. Also present at excitatory synapses.
- Information by UniProt
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All lanes : Anti-PICK1 antibody [EPR4130(3)] (ab133773) at 1/1000 dilution
Lane 1 : Human fetal brain lysate
Lane 2 : LnCaP lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled Goat anti Rabbit IgG at 1/2000 dilution
Predicted band size: 46 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
ab133773 has not yet been referenced specifically in any publications.