Key features and details
- Mouse monoclonal [002-18] to PICP
- Suitable for: ELISA, Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-PICP antibody [002-18]
See all PICP primary antibodies
DescriptionMouse monoclonal [002-18] to PICP
Specificityab76102 is specific for native PICP from amniotic fluid.
Tested applicationsSuitable for: ELISA, Sandwich ELISAmore details
Species reactivityReacts with: Human
PICP purified from second trimester amniotic fluid by affinity chromatography
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 2.9% Sodium chloride, 0.0268% PBS
Concentration information loading...
Purification notesab76102 is protein A/G purified.
Light chain typekappa
sELISA pair antibody
Our Abpromise guarantee covers the use of ab76102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Sandwich ELISA||Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal  to PICP (ab17202). Use as Detection antibody with recommended pair.|
FunctionType I collagen is a member of group I collagen (fibrillar forming collagen).
Tissue specificityForms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Involvement in diseaseCaffey disease
Ehlers-Danlos syndrome 1
Ehlers-Danlos syndrome 7A
Osteogenesis imperfecta 1
Osteogenesis imperfecta 2
Osteogenesis imperfecta 3
Osteogenesis imperfecta 4
A chromosomal aberration involving COL1A1 is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF.
Sequence similaritiesBelongs to the fibrillar collagen family.
Contains 1 fibrillar collagen NC1 domain.
Contains 1 VWFC domain.
DomainThe C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function.
modificationsProline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.
O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group.
Cellular localizationSecreted > extracellular space > extracellular matrix.
- Information by UniProt
- COL1A1 antibody
- Alpha 1 type I collagen antibody
- Alpha-1 type I collagen antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab76102 has not yet been referenced specifically in any publications.