Overview

  • Product name
    Pifithrin-alpha-HBr, p53 Inhibitor
  • Description
    p53 Inhibitor
  • Purity
    > 98%
  • General notes

    Pifithrin-?-HBr is light senstive and it is recommended that the compound is protected from light.

  • CAS Number
    63208-82-2
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Sohn D  et al. Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53. Cell Death Differ 16:869-78 (2009). Read more (PubMed: 19229248) »
  • Hoagland MS  et al. The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor. J Pharmacol Exp Ther 314:603-10 (2005). Read more (PubMed: 15843497) »
  • Komarova EA  et al. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways. J Biol Chem 278:15465-8 (2003). Read more (PubMed: 12637507) »
  • Komarov PG  et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285:1733-7 (1999). Read more (PubMed: 10481009) »
See 1 Publication for this product

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