Overview

  • Product name
    Pifithrin-mu, Inhibitor of p53-mediated apoptosis
  • Description
    Inhibitor of p53-mediated apoptosis
  • Alternative names
    • NSC 303580
  • Biological description
    An inhibitor of p53-mediated apoptosis. Prevents p53 binding at the mitochondrial surface without affecting p53 transactivational activities. Pifithrin-μ reduces p53-mediated apoptosis triggered by nutlin; also interacts selectively with HSP70, disrupting its association with many substrate proteins.
  • Purity
    > 98%
  • CAS Number
    64984-31-2
  • Chemical structure
    Chemical Structure

Properties

References

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