Overview

  • Product name

  • Description

    Rabbit polyclonal to Pin1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, IP, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human Pin1 (internal sequence).
    Database link: Q13526

  • Positive control

    • Human testis tissue; HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab191271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
IP 1/100.
WB 1/500 - 1/3000. Predicted molecular weight: 18 kDa.

Target

  • Function

    Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.
  • Sequence similarities

    Contains 1 PpiC domain.
    Contains 1 WW domain.
  • Domain

    The WW domain is required for the interaction with STIL and KIF20B.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • DOD antibody
    • DODO, Drosophila, homolog of antibody
    • FLJ40239 antibody
    • FLJ77628 antibody
    • MGC10717 antibody
    • NIMA interacting 1 antibody
    • Peptidyl prolyl cis trans isomerase NIMA interacting 1 antibody
    • Peptidyl prolyl cis/trans isomerase NIMA interacting antibody
    • Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody
    • Peptidyl-prolyl cis-trans isomerase pin1 antibody
    • Peptidylprolyl cis/trans isomerase NIMA interacting 1 antibody
    • Pin 1 antibody
    • Pin1 antibody
    • PIN1_HUMAN antibody
    • PPIase Pin1 antibody
    • Prolyl isomerase antibody
    • Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody
    • Protein NIMA interacting 1 antibody
    • Rotamase Pin1 antibody
    • UBL 5 antibody
    • UBL5 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded, formalin-fixed Human testis tissue labeling Pin1 using ab191271 at 5 µg/ml.

  • All lanes : Anti-Pin1 antibody (ab191271) at 1/700 dilution

    All lanes : HeLa cell lysate

    Secondary
    All lanes : HRP Goat-anti-Rabbit IgG at 1/5000 dilution

    Developed using the ECL technique.

    Predicted band size: 18 kDa


    Exposure time: 15 seconds


    15% SDS Page. 15 seconds exposure time.

References

ab191271 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab191271.
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