Overview

  • Product name

    Pioglitazone hydrochloride, PPAR-gamma agonist
  • Description

    Selective PPAR-γ agonist
  • Biological description

    Selective PPAR-γ agonist (EC50 values are 280, >1000 and >1000 nM for PPAR isoforms γ, α and δ, respectively). Antidiabetic activities in vivo, improves the response to circulating insulin.

  • Purity

    > 99%
  • CAS Number

    112529-15-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Heneka MT  et al. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain 128:1442-53 (2005). Read more (PubMed: 15817521) »
  • Xu HE  et al. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 98:13919-24 (2001). Read more (PubMed: 11698662) »
  • Colca JR  et al. Pioglitazone hydrochloride inhibits cholesterol absorption and lowers plasma cholesterol concentrations in cholesterol-fed rats. Diabetes 40:1669-74 (1991). Read more (PubMed: 1756906) »
See 1 Publication for this product

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