Product nameAnti-PIP2 antibody
See all PIP2 primary antibodies
DescriptionMouse monoclonal to PIP2
SpecificityThis antibody cross reacts with Phosphatidic acid (<5.0%).
Tested applicationsSuitable for: ICC/IFmore details
Phosphatidylinositol-4,5-biphosphate (PIP2) from bovine spinal cord
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: PBS, 10% Fetal calf serum
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab2335 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration.
TBS buffer is ideal.
RelevancePhosphatidylinositol 4,5-biphosphate (PIP2) is a membrane phospholipid that has been implicated in a variety of cellular processes, including synaptic vesicle recycling and signal transduction pathways. PLCD4 hydrolyzes PIP2 to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).
This product has been referenced in:
- Wahl S et al. The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses. J Neurosci 36:2473-93 (2016). Read more (PubMed: 26911694) »
- Li J et al. Actin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy. Am J Physiol Heart Circ Physiol 307:H1618-25 (2014). Read more (PubMed: 25260617) »