Pirfenidone, orally active anti-inflammatory antifibrotic agent (ab141425)

Overview

  • Product name
    Pirfenidone, orally active anti-inflammatory antifibrotic agent
  • Description
    Orally active anti-inflammatory antifibrotic agent
  • Biological description
    Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.
  • Purity
    > 99%
  • CAS Number
    53179-13-8
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Hisatomi K  et al. Pirfenidone inhibits TGF-ß1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells. BMC Pulm Med 12:24 (2012). Read more (PubMed: 22694981) »
  • Shi Q  et al. In vitro effects of pirfenidone on cardiac fibroblasts: proliferation, myofibroblast differentiation, migration and cytokine secretion. PLoS One 6:e28134 (2011). Read more (PubMed: 22132230) »
  • Walker JE & Margolin SB Pirfenidone for chronic progressive multiple sclerosis. Mult Scler 7:305-12 (2001). Read more (PubMed: 11724446) »
See 1 Publication for this product

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