Key features and details
- Orally active anti-inflammatory antifibrotic agent
- CAS Number: 53179-13-8
- Purity: > 99%
- Soluble in 1 eq. HCl to 100 mM and in water to 25 mM
- Form / State: Solid
- Source: Synthetic
Product namePirfenidone, orally active anti-inflammatory antifibrotic agent
DescriptionOrally active anti-inflammatory antifibrotic agent
Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable. Shown to modulate cytokines TGF-β and TNF-α.
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 1 eq. HCl to 100 mM and in water to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141425 has been referenced in 1 publication.
- Westermeyer HD et al. Safety and efficacy of topically applied 0.5% and 1% pirfenidone in a canine model of subconjunctival fibrosis. Vet Ophthalmol N/A:N/A (2019). PubMed: 30701645