Recombinant Anti-Pirh2 antibody [EPR18553] - BSA and Azide free (ab251001)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Pirh2 antibody [EPR18553] - BSA and Azide free
See all Pirh2 primary antibodies -
Description
Rabbit monoclonal [EPR18553] to Pirh2 - BSA and Azide free -
Host species
Rabbit -
Tested applications
Suitable for: WB, IP, ICC/IFmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide within Human Pirh2 aa 150-250. The exact sequence is proprietary.
Database link: Q96PM5 -
General notes
Ab251001 is the carrier-free version of ab189907. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
ab251001 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: PBS -
Carrier free
Yes -
Concentration information loading... -
Clonality
Monoclonal -
Clone number
EPR18553 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Related Products
Applications
Our Abpromise guarantee covers the use of ab251001 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa). | |
| IP | Use at an assay dependent concentration. | |
| ICC/IF | Use at an assay dependent concentration. |
Target
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Function
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. -
Pathway
Protein modification; protein ubiquitination. -
Sequence similarities
Contains 1 CHY-type zinc finger.
Contains 1 CTCHY-type zinc finger.
Contains 1 RING-type zinc finger. -
Post-translational
modificationsSubject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability. -
Cellular localization
Nucleus. Nucleus speckle. Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 25898 Human
- Entrez Gene: 68098 Mouse
- Omim: 607680 Human
- SwissProt: Q96PM5 Human
- SwissProt: Q9CR50 Mouse
- Unigene: 48297 Human
- Unigene: 159453 Mouse
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Alternative names
- Androgen receptor N terminal interacting protein antibody
- Androgen receptor N-terminal-interacting protein antibody
- ARNIP antibody
see all
Datasheets and documents
References
ab251001 has not yet been referenced specifically in any publications.
