Overview

  • Product name
    Piroxicam, cyclooxygenase-1 (COX-1) inhibitor
  • Description
    Reversible, selective cyclooxygenase-1 (COX-1) inhibitor
  • Biological description
    Reversible, selective cyclooxygenase-1 (COX-1) inhibitor. Shows 8-fold greater activity against COX-1 than COX-2 (IC50 values are 0.76 and 8.99 μM for COX-1 and COX-2, respectively).
  • Purity
    > 99%
  • CAS Number
    36322-90-4
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Buharalioglu CK  et al. Piroxicam reverses endotoxin-induced hypotension in rats: contribution of vasoactive eicosanoids and nitric oxide. Basic Clin Pharmacol Toxicol 109:186-94 (2011). Read more (PubMed: 21463481) »
  • Dannhardt G & Kiefer W Cyclooxygenase inhibitors--current status and future prospects. Eur J Med Chem 36:109-26 (2001). Read more (PubMed: 11311743) »
  • Blanco FJ  et al. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes. J Rheumatol 26:1366-73 (1999). Read more (PubMed: 10381057) »

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