Overview

  • Product name

    Anti-PKA R2/PKR2 (phospho S96) antibody
    See all PKA R2/PKR2 primary antibodies
  • Description

    Rabbit polyclonal to PKA R2/PKR2 (phospho S96)
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide within Human PKA R2/PKR2 (N terminal). The exact sequence is proprietary. Conjugated to a carrier protein.
    Database link: P13861

  • Positive control

    • WB: HEK-293T whole cell extracts.
  • General notes

     This product was previously labelled as PKA R2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab226754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.

Target

  • Function

    Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
  • Tissue specificity

    Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
  • Sequence similarities

    Belongs to the cAMP-dependent kinase regulatory chain family.
    Contains 2 cyclic nucleotide-binding domains.
  • Post-translational
    modifications

    Phosphorylated by the activated catalytic chain.
  • Cellular localization

    Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and the cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • cAMP dependent protein kinase regulatory subunit alpha 2 antibody
    • cAMP dependent protein kinase regulatory subunit RII alpha antibody
    • cAMP dependent protein kinase type II alpha regulatory chain antibody
    • cAMP dependent protein kinase type II alpha regulatory subunit antibody
    • cAMP-dependent protein kinase type II-alpha regulatory subunit antibody
    • KAP2 antibody
    • KAP2_HUMAN antibody
    • MGC3606 antibody
    • PKR 2 antibody
    • PKR2 antibody
    • PRKA R2 antibody
    • PRKAR 2 antibody
    • PRKAR2 antibody
    • PRKAR2A antibody
    • Protein kinase A RII alpha subunit antibody
    • Protein kinase cAMP dependent regulatory type II alpha antibody
    see all

Images

  • All lanes : Anti-PKA R2/PKR2 (phospho S96) antibody (ab226754) at 1/3000 dilution

    Lane 1 : Untreated HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extracts
    Lane 2 : CIP treated HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extracts

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 46 kDa

References

ab226754 has not yet been referenced specifically in any publications.

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