PKC epsilon peptide (ab204875)
- Datasheet
- References
- Protocols
Description
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Product name
PKC epsilon peptide
See all PKC epsilon proteins and peptides -
Animal free
No -
Nature
Synthetic -
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Sequence
ERMRPRKRQGSVRRRV
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Associated products
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Recombinant Protein
- Recombinant human KDS protein (ab125551)
- Recombinant human MST3 protein (ab51413)
- Recombinant human PKC theta/PRKCQ protein (ab56641)
- Recombinant human PKC beta 1 protein (ab60840)
- Recombinant human PKC gamma protein (ab60842)
- Recombinant human PKC epsilon protein (ab60847)
- Recombinant human PKC eta protein (ab60849)
- Recombinant human STK23 protein (ab84801)
Specifications
Our Abpromise guarantee covers the use of ab204875 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
HPLC
Functional Studies
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Form
Lyophilised -
Additional notes
ab204875 (PKC epsilon peptide) can be utilized as a substrate for the following active protein kinases:
ab60840 (Active human PKC beta 1 full length protein)
ab60847 (Active human PKC epsilon full length protein)
ab60842 (Active human PKC gamma full length protein)
ab60849 (Active human PKC eta full length protein)
ab56641 (Active human PKC theta full length protein)
ab84801 (Active human STK23 full length protein)
ab51413 (Active human MST3 protein fragment)
ab125551 (Active human JIK protein fragment) -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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ReconstitutionDilute peptide in distilled water to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.
General Info
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Alternative names
- KPCE_HUMAN
- MGC125656
- MGC125657
see all -
Function
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. -
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 C2 domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Contains 1 protein kinase domain. -
Domain
The C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain. -
Post-translational
modificationsPhosphorylation on Thr-566 by PDPK1 triggers autophosphorylation on Ser-729. - Information by UniProt
Datasheets and documents
References
ab204875 has not yet been referenced specifically in any publications.
