Anti-PKC eta antibody (ab167482)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-PKC eta antibody
See all PKC eta primary antibodies -
Description
Mouse polyclonal to PKC eta -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Cow, Dog
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Immunogen
Full length Human PKC eta (amino acids 1-683; NP_006246.2).
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Positive control
- PKC eta transfected 293T cell lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.20
Constituent: 99% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab167482 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa. |
Target
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Function
This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. -
Tissue specificity
Most abundant in lung, less in heart and skin. -
Involvement in disease
Defects in PRKCH may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. -
Sequence similarities
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 C2 domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Contains 1 protein kinase domain. -
Domain
The C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain. - Information by UniProt
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Database links
- Entrez Gene: 518542 Cow
- Entrez Gene: 100051560 Horse
- Entrez Gene: 5583 Human
- Entrez Gene: 18755 Mouse
- Entrez Gene: 81749 Rat
- Omim: 605437 Human
- SwissProt: P24723 Human
- SwissProt: P23298 Mouse
see all -
Alternative names
- KPCL_HUMAN antibody
- MGC 5363 antibody
- MGC26269 antibody
see all
Images
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Western blot - Anti-PKC eta antibody (ab167482)All lanes : Anti-PKC eta antibody (ab167482) at 1 µg/ml
Lane 1 : PKC eta transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 78 kDa
Protocols
Datasheets and documents
References
ab167482 has not yet been referenced specifically in any publications.
