Overview

  • Product name

    Anti-PKC mu/PKD antibody [EPR1492(2)]
    See all PKC mu/PKD primary antibodies
  • Description

    Rabbit monoclonal [EPR1492(2)] to PKC mu/PKD
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human PKC mu/PKD aa 200-300.

  • Positive control

    • HeLa, Jurkat, HepG2, and K562 cell lysates
  • General notes

    A trial size is available to purchase for this antibody.

     

     This product was previously labelled as PKC mu

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab108963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 105 kDa (predicted molecular weight: 102 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
    • Sequence similarities

      Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
      Contains 1 PH domain.
      Contains 2 phorbol-ester/DAG-type zinc fingers.
      Contains 1 protein kinase domain.
    • Cellular localization

      Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
    • Information by UniProt
    • Database links

    • Alternative names

      • KPCD1_HUMAN antibody
      • nPKC D1 antibody
      • nPKC mu antibody
      • nPKC-D1 antibody
      • nPKC-mu antibody
      • nPKCD1 antibody
      • nPKCmu antibody
      • PKC antibody
      • PKC MU antibody
      • PKCM antibody
      • PKCmu antibody
      • PKD 1 antibody
      • PKD antibody
      • PKD1 antibody
      • PRKCM antibody
      • PRKD 1 antibody
      • Prkd1 antibody
      • Protein kinase C mu antibody
      • Protein kinase C mu type antibody
      • Protein kinase D antibody
      • Protein kinase D1 antibody
      • Serine/threonine protein kinase D1 antibody
      • Serine/threonine-protein kinase D1 antibody
      see all

    Images

    • All lanes : Anti-PKC mu/PKD antibody [EPR1492(2)] (ab108963) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : HepG2 cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 102 kDa

    References

    This product has been referenced in:

    • Sehgal L  et al. 14-3-3?-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci 127:2174-88 (2014). Mouse, Human . Read more (PubMed: 24610948) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab108963.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up