Overview

  • Product name

    Anti-PKC mu/PKD (phospho S205) antibody
    See all PKC mu/PKD primary antibodies
  • Description

    Rabbit polyclonal to PKC mu/PKD (phospho S205)
  • Host species

    Rabbit
  • Specificity

    Detects endogenous levels of PKC µ/PKD only when phosphorylated at serine 205 if Human or serine 203 if Mouse.

  • Tested applications

    Suitable for: IHC-P, ELISAmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human PKC mu/PKD.

  • Positive control

    • Brain tissue
  • General notes

     This product was previously labelled as PKC mu

     

Properties

Applications

Our Abpromise guarantee covers the use of ab59413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/40000.

Target

  • Function

    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • Cellular localization

    Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt
  • Database links

  • Alternative names

    • KPCD1_HUMAN antibody
    • nPKC D1 antibody
    • nPKC mu antibody
    • nPKC-D1 antibody
    • nPKC-mu antibody
    • nPKCD1 antibody
    • nPKCmu antibody
    • PKC antibody
    • PKC MU antibody
    • PKCM antibody
    • PKCmu antibody
    • PKD 1 antibody
    • PKD antibody
    • PKD1 antibody
    • PRKCM antibody
    • PRKD 1 antibody
    • Prkd1 antibody
    • Protein kinase C mu antibody
    • Protein kinase C mu type antibody
    • Protein kinase D antibody
    • Protein kinase D1 antibody
    • Serine/threonine protein kinase D1 antibody
    • Serine/threonine-protein kinase D1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded human brain tissue using ab59413 at 1/50 dilution, in the presence (right) and absence (left) of immunising phosphopeptide.

References

This product has been referenced in:

  • Chang JK  et al. Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. J Biol Chem 292:9523-9539 (2017). Read more (PubMed: 28408623) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab59413.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up