Overview

  • Product name

    Anti-PKC mu/PKD (phospho S738) antibody
    See all PKC mu/PKD primary antibodies
  • Description

    Rabbit polyclonal to PKC mu/PKD (phospho S738)
  • Host species

    Rabbit
  • Specificity

    ab131101 detects endogenous levels of PKC mu/PKD only when phosphorylated at serine 738.

  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human PKC mu/PKD conjugated to keyhole limpet haemocyanin.
    Sequence:

    E-K-S(p)-F-R


    Database link: Q15139

  • Positive control

    • MCF cell extract untreated and treated with PMA; HeLa cells
  • General notes

     This product was previously labelled as PKC mu

     

Properties

Applications

Our Abpromise guarantee covers the use of ab131101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 115 kDa (predicted molecular weight: 102 kDa).
ICC/IF 1/100 - 1/200.

Target

  • Function

    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • Cellular localization

    Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt
  • Database links

  • Alternative names

    • KPCD1_HUMAN antibody
    • nPKC D1 antibody
    • nPKC mu antibody
    • nPKC-D1 antibody
    • nPKC-mu antibody
    • nPKCD1 antibody
    • nPKCmu antibody
    • PKC antibody
    • PKC MU antibody
    • PKCM antibody
    • PKCmu antibody
    • PKD 1 antibody
    • PKD antibody
    • PKD1 antibody
    • PRKCM antibody
    • PRKD 1 antibody
    • Prkd1 antibody
    • Protein kinase C mu antibody
    • Protein kinase C mu type antibody
    • Protein kinase D antibody
    • Protein kinase D1 antibody
    • Serine/threonine protein kinase D1 antibody
    • Serine/threonine-protein kinase D1 antibody
    see all

Images

  • All lanes : Anti-PKC mu/PKD (phospho S738) antibody (ab131101) at 1/500 dilution

    Lane 1 : MCF cell extract untreated
    Lane 2 : MCF cell extract treated with PMA

    Predicted band size: 102 kDa
    Observed band size: 115 kDa
    why is the actual band size different from the predicted?

  • Immunofluorescence analysis of methanol-fixed HeLa cells labelling PKC mu/PKD (phospho S738) with ab131101 at 1/100 dilution.

References

ab131101 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131101.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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