Overview

  • Product name

  • Description

    Rabbit polyclonal to PKIB
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human PKIB (internal sequence).
    Database link: Q9C010

  • Positive control

    • Human brain tissue; MCF7 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.87% Sodium chloride, 49% PBS

    PBS without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab196689 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196689 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/500.
IHC-P 1/50 - 1/100.

Target

  • Function

    Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
  • Sequence similarities

    Belongs to the PKI family.
  • Information by UniProt
  • Database links

  • Alternative names

    • cAMP dependent protein kinase inhibitor 2 antibody
    • cAMP-dependent protein kinase inhibitor beta antibody
    • FLJ23817 antibody
    • IPKB_HUMAN antibody
    • OTTHUMP00000017115 antibody
    • OTTHUMP00000017116 antibody
    • OTTHUMP00000017117 antibody
    • PKI-beta antibody
    • PKIB antibody
    • PRKACN2 antibody
    • Protein kinase (cAMP dependent, catalytic) inhibitor beta antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling PKIB with ab196689 at 1/50 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.

  • Immunofluorescent analysis of MCF7 cells labeling PKIB with ab196689 at 1/100 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.

References

This product has been referenced in:

  • Qin M  et al. Expression of S100A8 is induced by interleukin-1a in TR146 epithelial cells through a mechanism involving CCAAT/enhancer binding protein ß. Mol Med Rep 19:2413-2420 (2019). Read more (PubMed: 30664211) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab196689.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up