Overview

  • Product name

  • Description

    Rabbit polyclonal to PLA1A/NMD
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PLA1A/NMD (internal sequence).
    Database link: Q53H76

  • Positive control

    • Human brain tissue.
  • General notes

     This product was previously labelled as PLA1A

     

Properties

Applications

Our Abpromise guarantee covers the use of ab196794 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.

Target

  • Function

    Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
  • Tissue specificity

    Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
  • Sequence similarities

    Belongs to the AB hydrolase superfamily. Lipase family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AA986889 antibody
    • NMD antibody
    • OTTHUMP00000215248 antibody
    • OTTHUMP00000215249 antibody
    • OTTHUMP00000215250 antibody
    • Phosphatidylserine specific phospholipase A1 antibody
    • Phosphatidylserine specific phospholipase A1alpha antibody
    • Phosphatidylserine-specific phospholipase A1 antibody
    • Phospholipase A1 member A antibody
    • pla1a antibody
    • PLA1A_HUMAN antibody
    • PS PLA1 antibody
    • PS-PLA1 antibody
    • PSPLA 1 antibody
    • PSPLA1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling PLA1A/NMD with ab196794 at 1/50 dilution. The image on the right has been pre-incubated with the blocking peptide.

References

ab196794 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab196794.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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