Overview

  • Product name

    Anti-PLA2G5 antibody [3G1]
    See all PLA2G5 primary antibodies
  • Description

    Mouse monoclonal [3G1] to PLA2G5
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Full length protein corresponding to Human PLA2G5.

  • Positive control

    • Mouse macrophages.
  • General notes

     This product was previously labelled as Secretory phospholipase A2 Type V

     

Applications

Our Abpromise guarantee covers the use of ab111959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 15 kDa (predicted molecular weight: 16 kDa).

Target

  • Function

    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L-alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
  • Tissue specificity

    Heart, placenta and less abundantly, in lung.
  • Sequence similarities

    Belongs to the phospholipase A2 family.
  • Post-translational
    modifications

    This enzyme lacks one of the seven disulfide bonds found in similar PA2 proteins.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Ca2+ dependent phospholipase A2 antibody
    • Calcium dependent phospholipase A2 antibody
    • Calcium-dependent phospholipase A2 antibody
    • DKFZp686C2294 antibody
    • FRFB antibody
    • Group V phospholipase A2 antibody
    • GV PLA2 antibody
    • gVPLA2 antibody
    • hVPLA(2) antibody
    • MGC46205 antibody
    • OTTHUMP00000044655 antibody
    • PA2G5_HUMAN antibody
    • Phosphatidylcholine 2 acylhydrolase antibody
    • Phosphatidylcholine 2-acylhydrolase 5 antibody
    • Phospholipase A2 group V antibody
    • PLA2 10 antibody
    • PLA2 G5 antibody
    • PLA2-10 antibody
    • Pla2g5 antibody
    • sPLA2 Type V antibody
    see all

References

This product has been referenced in:

  • Muñoz NM  et al. Characterization of monoclonal antibodies specific for 14-kDa human group V secretory phospholipase A2 (hVPLA2). Hybridoma 19:171-6 (2000). Read more (PubMed: 10868798) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for contacting Abcam.


The antibody should be completely fine being stored at -20C and changing the storage temp from -80C to -20C will not affect the performance of the antibody.

If there is anything elseIcan help you with, please let me know.

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