Anti-PLA2G5 antibody (ab23709)
Key features and details
- Rabbit polyclonal to PLA2G5
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-PLA2G5 antibody -
Description
Rabbit polyclonal to PLA2G5 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide corresponding to Mouse PLA2G5 aa 79-94 conjugated to keyhole limpet haemocyanin.
Sequence:CAIRTQSYDY RYTNGL
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 50% Glycerol, 0.05% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab23709 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500. Predicted molecular weight: 15 kDa.
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Notes |
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WB
1/500. Predicted molecular weight: 15 kDa. |
Target
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Function
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L-alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle. -
Tissue specificity
Heart, placenta and less abundantly, in lung. -
Sequence similarities
Belongs to the phospholipase A2 family. -
Post-translational
modificationsThis enzyme lacks one of the seven disulfide bonds found in similar PA2 proteins. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 5322 Human
- Entrez Gene: 18784 Mouse
- Omim: 601192 Human
- SwissProt: P39877 Human
- SwissProt: P97391 Mouse
- Unigene: 319438 Human
- Unigene: 23347 Mouse
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Alternative names
- Ca2+ dependent phospholipase A2 antibody
- Calcium dependent phospholipase A2 antibody
- Calcium-dependent phospholipase A2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab23709 has been referenced in 2 publications.
- Watanabe K et al. Group V secreted phospholipase A2 plays a protective role against aortic dissection. J Biol Chem 295:10092-10111 (2020). PubMed: 32482892
- Zhu S et al. High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA2-IIE and sPLA2-V Expression in Macrophages. PLoS One 11:e0167468 (2016). WB ; Mouse . PubMed: 27898742