This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 50 kDa.

Preliminary experiments gave an approx 100kDa band in human liver lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 50.1kDa according to NP_005075.3. The 100kDa band was successfully blocked by incubation with the immunizing peptide.

Target

  • Function
    Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.
  • Tissue specificity
    Plasma.
  • Involvement in disease
    Platelet-activating factor acetylhydrolase deficiency
    Asthma
    Atopic hypersensitivity
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Lipase family.
  • Cellular localization
    Secreted, extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • Platelet-activating factor acetylhydrolase precursor antibody
    • 1 alkyl 2 acetylglycerophosphocholine esterase antibody
    • 1-alkyl-2-acetylglycerophosphocholine esterase antibody
    • 2 acetyl 1 alkylglycerophosphocholine esterase antibody
    • 2-acetyl-1-alkylglycerophosphocholine esterase antibody
    • EC 3.1.1.47 PAF acetylhydrolase PAF 2-acylhydrolase LDL associated phospholipase A2 antibody
    • Group VIIA phospholipase A2 antibody
    • Group-VIIA phospholipase A2 antibody
    • gVIIA PLA2 antibody
    • gVIIA-PLA2 antibody
    • LDL associated phospholipase A2 antibody
    • LDL PLA(2) antibody
    • LDL PLA2 antibody
    • LDL-associated phospholipase A2 antibody
    • LDL-PLA(2) antibody
    • Lipoprotein associated phospholipase A2 antibody
    • LP PLA2 antibody
    • PAF 2 acylhydrolase antibody
    • PAF 2 acylhydrolase LDL associated phospholipase A2 antibody
    • PAF 2-acylhydrolase antibody
    • PAF acetylhydrolase antibody
    • PAFA_HUMAN antibody
    • PAFAD antibody
    • PAFAH antibody
    • Phospholipase A2, group VII (platelet activating factor acetylhydrolase, plasma) antibody
    • PLA2G7 antibody
    • Platelet activating factor acetylhydrolase 2 antibody
    • Platelet activating factor acetylhydrolase antibody
    • Platelet-activating factor acetylhydrolase antibody
    see all

References

ab169836 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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