Overview

  • Product name

    Anti-Plakophilin 2/PKP2 antibody
    See all Plakophilin 2/PKP2 primary antibodies
  • Description

    Rabbit polyclonal to Plakophilin 2/PKP2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Horse, Cat
  • Immunogen

    Synthetic peptide corresponding to Human Plakophilin 2/PKP2 aa 143-192 (N terminal).
    Sequence:

    HPLRRLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHHQESRRAALLVPP


    Database link: NP_001005242

  • Positive control

    • COLO205 cell lysate
  • General notes

     This product was previously labelled as Plakophilin 2

     

Properties

Applications

Our Abpromise guarantee covers the use of ab98328 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 93 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    May play a role in junctional plaques.
  • Tissue specificity

    Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
  • Involvement in disease

    Familial arrhythmogenic right ventricular dysplasia 9
  • Sequence similarities

    Belongs to the beta-catenin family.
    Contains 8 ARM repeats.
  • Cellular localization

    Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.
  • Information by UniProt
  • Database links

  • Alternative names

    • ARVD 9 antibody
    • ARVD9 antibody
    • PKP 2 antibody
    • PKP2 antibody
    • PKP2_HUMAN antibody
    • Plakophilin-2 antibody
    • Plakophilin2 antibody
    see all

Images

  • Anti-Plakophilin 2/PKP2 antibody (ab98328) at 1 µg/ml (in 5% skim milk / PBS buffer) + COLO205 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 93 kDa



    Gel concentration: 6-18%

References

ab98328 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab98328.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up