Anti-Plakophilin 3 antibody [7F6] (ab151401)
Key features and details
- Mouse monoclonal [7F6] to Plakophilin 3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-Plakophilin 3 antibody [7F6]
See all Plakophilin 3 primary antibodies -
Description
Mouse monoclonal [7F6] to Plakophilin 3 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to amino acids 1-308 of Human Plakophilin 3 fused to maltose binding protein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
7F6 -
Myeloma
NS1 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab151401 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/100. Predicted molecular weight: 87 kDa.
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Notes |
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WB
1/100. Predicted molecular weight: 87 kDa. |
Target
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Function
May play a role in junctional plaques. -
Tissue specificity
Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues. -
Sequence similarities
Belongs to the beta-catenin family.
Contains 8 ARM repeats. -
Cellular localization
Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes. - Information by UniProt
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Database links
- Entrez Gene: 11187 Human
- Omim: 605561 Human
- SwissProt: Q9Y446 Human
- Unigene: 534395 Human
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Alternative names
- PKP 3 antibody
- PKP3 antibody
- PKP3_HUMAN antibody
see all
Images
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Anti-Plakophilin 3 antibody [7F6] (ab151401) at 1/100 dilution + HaCat Human keratinocyte cells
Predicted band size: 87 kDa
Observed band size: 90 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab151401 has been referenced in 3 publications.
- Ahmad US et al. Desmoglein-3 induces YAP phosphorylation and inactivation during collective migration of oral carcinoma cells. Mol Oncol 16:1625-1649 (2022). PubMed: 35000271
- Flemming S et al. Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration. Mol Biol Cell 31:407-418 (2020). PubMed: 31967937
- Uttagomol J et al. Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces. Int J Mol Sci 20:N/A (2019). PubMed: 31835537