Product nameAnti-Plasma Kallikrein 1B antibody
See all Plasma Kallikrein 1B primary antibodies
DescriptionRabbit polyclonal to Plasma Kallikrein 1B
Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment corresponding to Human Plasma Kallikrein 1B (N terminal).
Database link: P03952
- Mouse liver, intestine and brain extracts; HeLa cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.87% Sodium chloride, 50% Glycerol
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab196555 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 71 kDa.|
|ICC/IF||1/50 - 1/200.|
|IHC-P||1/50 - 1/200.|
FunctionThe enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Involvement in diseaseDefects in KLKB1 are the cause of prekallikrein deficiency (PKK deficiency) [MIM:612423]; also known as Fletcher factor deficiency. This disorder is a blood coagulation defect.
Sequence similaritiesBelongs to the peptidase S1 family. Plasma kallikrein subfamily.
Contains 4 apple domains.
Contains 1 peptidase S1 domain.
- Information by UniProt
- Fletcher factor antibody
- kallikrein B plasma antibody
- Kallikrein B plasma (Fletcher factor) 1 antibody
All lanes : Anti-Plasma Kallikrein 1B antibody (ab196555) at 1/500 dilution
Lane 1 : Mouse liver extract
Lane 2 : Mouse intestine extract
Lane 3 : Mouse brain extract
Predicted band size: 71 kDa
Immunofluorescence analysis of HeLa cells, labeling Plasma Kallikrein 1B (green) with ab196555 at 1/50 dilution. Nuclei were counterstained with DAPI (blue).
ab196555 has not yet been referenced specifically in any publications.