Anti-PLEKHG4 antibody (ab137898)
Key features and details
- Rabbit polyclonal to PLEKHG4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PLEKHG4 antibody
See all PLEKHG4 primary antibodies -
Description
Rabbit polyclonal to PLEKHG4 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide derived from an internal region of Human PLEKHG4.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine)
PBS is without Mg2+ and Ca2+ -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137898 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 131 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 131 kDa. |
Target
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Function
Possible role in intracellular signaling and cytoskeleton dynamics at the Golgi. -
Tissue specificity
Expressed in kidney, Leydig cells in the testis, epithelial cells in the prostate gland and Langerhans islet in the pancreas. Isoform 1 and isoform 3 are strongly expressed in Purkinje cells and to a lower extent in other neurons (at protein level). Widely expressed at low levels. More strongly expressed in testis and pancreas. -
Sequence similarities
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain. - Information by UniProt
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Database links
- Entrez Gene: 25894 Human
- Omim: 609526 Human
- SwissProt: Q58EX7 Human
- Unigene: 188781 Human
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Alternative names
- ARHGEF44 antibody
- DKFZp434I216 antibody
- PH domain containing family G member 4 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab137898 has been referenced in 2 publications.
- Takenaka N et al. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS One 11:e0155292 (2016). PubMed: 27163697
- Gupta M et al. Plekhg4 is a novel Dbl family guanine nucleotide exchange factor protein for rho family GTPases. J Biol Chem 288:14522-30 (2013). IHC-P ; Mouse . PubMed: 23572525