Overview

  • Product name

  • Description

    Rabbit polyclonal to Plexin B1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide derived from Human Plexin B1.

  • Positive control

    • Human liver tissue; HeLa cell membrane extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab136880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200. Detects a band of approximately 200, 250 kDa (predicted molecular weight: 232 kDa).
ELISA 1/10000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    Plexin B1 is the transmembrane receptor for the class 4 semaphorin, SEMA4D. Plexin B1 activation plays a role in axon guidance, invasive growth and cell migration and has been reported to have additional roles in RHOA activation and subsequent changes of the actin cytoskeleton.
  • Cellular localization

    Secreted and single pass type I membrane protein.
  • Database links

  • Alternative names

    • KIAA0407 antibody
    • Plexin 5 antibody
    • Plexin B1 antibody
    • PLXN5 antibody
    • PLXNB1 antibody
    • Semaphorin receptor antibody
    • Semaphorin receptor SEP antibody
    • SEP antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labelling Plexin B1 with ab136880 at 5µg/ml.
  • Anti-Plexin B1 antibody (ab136880) at 1/300 dilution + HeLa cell membrane extract

    Predicted band size: 232 kDa



    The higher band represents Plexin B1 precursor and the lower band Plexin B1 cleavage product.

References

ab136880 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab136880.
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