Overview

  • Product name

    Anti-PLGF antibody [EPR2802(2)]
    See all PLGF primary antibodies
  • Description

    Rabbit monoclonal [EPR2802(2)] to PLGF
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PLGF aa 50-150. The exact sequence is proprietary.

  • Positive control

    • JAR cell lysate; recombinant Human PLGF protein.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab140639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 25 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner.
    • Tissue specificity

      While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas.
    • Sequence similarities

      Belongs to the PDGF/VEGF growth factor family.
    • Domain

      Isoform PlGF-2 contains a basic insert which acts as a cell retention signal.
    • Post-translational
      modifications

      N-glycosylated.
    • Cellular localization

      Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin.
    • Information by UniProt
    • Database links

    • Alternative names

      • D12S1900 antibody
      • Pgf antibody
      • PGFL antibody
      • PIGF antibody
      • Placenta growth factor antibody
      • Placental growth factor antibody
      • Placental growth factor, vascular endothelial growth factor related protein antibody
      • PlGF 2 antibody
      • PlGF antibody
      • PLGF_HUMAN antibody
      • PlGF2 antibody
      • SHGC 10760 antibody
      see all

    Images

    • Anti-PLGF antibody [EPR2802(2)] (ab140639) at 1/1000 dilution + JAR cell lysate at 10 µg

      Predicted band size: 25 kDa

    • Anti-PLGF antibody [EPR2802(2)] (ab140639) at 1/1000 dilution + Recombinant Human PLGF at 0.005 µg

      Predicted band size: 25 kDa

    References

    ab140639 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140639.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

    Sign up