Anti-PLP2 antibody (ab122792)
Key features and details
- Rabbit polyclonal to PLP2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-PLP2 antibody
See all PLP2 primary antibodies -
Description
Rabbit polyclonal to PLP2 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence: RGNHSKIVAG VKAMGAALKH RAKGLRSQGP FLP, corresponding to C terminal amino acids 106-138 of Human PLP2 (isoform 2).
-
Positive control
- Human cerebellum tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
Notes |
---|
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
May play a role in cell differentiation in the intestinal epithelium. -
Tissue specificity
Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt. -
Sequence similarities
Contains 1 MARVEL domain. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 5355 Human
- Omim: 300112 Human
- SwissProt: Q04941 Human
- Unigene: 77422 Human
-
Alternative names
- A4 antibody
- A4 differentiation dependent protein antibody
- A4-LSB antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab122792 has been referenced in 1 publication.
- Xiao W et al. MiR-765 functions as a tumour suppressor and eliminates lipids in clear cell renal cell carcinoma by downregulating PLP2. EBioMedicine 51:102622 (2020). PubMed: 31901870