Key features and details
- Rabbit polyclonal to PLRG1
- Suitable for: IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-PLRG1 antibody
See all PLRG1 primary antibodies
DescriptionRabbit polyclonal to PLRG1
Tested applicationsSuitable for: IHC-P, ICC/IFmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis, Platypus
Synthetic peptide, corresponding to a region between residues 464 and 514 of human PLRG1 (NP_002660.1)
- Human Anaplastic Thyroid Carcinoma, Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma, Small Cell Lung Cancer, Stomach Adenocarcinoma, Testicular Seminoma tissues. Mouse Renal Cell Carcinoma, Squamous Cell Carcinoma, Teratoma tissues
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab87268 was affinity purified using an epitope specific to PLRG1 immobilized on solid support.
Our Abpromise guarantee covers the use of ab87268 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/100 - 1/500 Epitope exposure with citrate or tris-EDTA pH 9.0 buffer will enhance staining.
Likely to work with frozen sections
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionNecessary for spliceosome assembly and for pre-mRNA splicing.
Sequence similaritiesBelongs to the WD repeat PRL1/PRL2 family.
Contains 7 WD repeats.
Cellular localizationNucleus speckle.
- Information by UniProt
- Cwc1 antibody
- MGC110980 antibody
- pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) antibody
ab87268 at 1/100 dilution staining PLRG1 in human breast carcinoma by Immunofluorescence, Formalin-fixed, Paraffin-embedded tissue. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte PlusTM 555 used at a dilution of 1/100.
ab87268 at 1/500 dilution staining PLRG1 in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
ab87268 at 1/100 dilution staining PLRG1 in human prostate carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
ab87268 at 1/100 dilution staining PLRG1 in mouse squamous cell carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
ab87268 has been referenced in 1 publication.
- de Moura TR et al. Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol Cell 69:979-992.e6 (2018). PubMed: 29547724